Panama neither bans crypto nor licenses it, and the two facts sit together. The Superintendencia del Mercado de Valores stated in Opinión 04-2025 of 27 August 2025 that cryptocurrencies such as ether and bitcoin are not among the products of the activities it supervises - investing for client account in securities, financial instruments and currencies - so regulating, supervising or overseeing crypto-related activity falls outside its competence, and a business built on custody and facilitation of crypto exchange needs no licence, registration or special authorisation from it.
A perpetual on UNI tracks price and does not confer ownership of the underlying — the same contract mechanics apply in every jurisdiction; what differs by country is legal status and funding rails.
11 venues open Uniswap perps to traders in Panama.
ApeX
Aster
gTrade
Helix
Hyperliquid
Lighter
Pacifica
Paradex
ReyaFour steps from sign-up to an open position.
The Dirección General de Ingresos states the general territorial principle: income tax is owed by whoever receives income from activities carried out in Panamanian territory, irrespective of nationality, domicile or residence, and the annual return covers income and the expenses originated or caused in Panama that produced the taxed profit.
Trading UNI from Panama: legal.
Regulator for Uniswap trading in Panama: Superintendencia del Mercado de Valores (SMV, securities), Superintendencia de Bancos de Panamá (SBP, banking) and Dirección General de Ingresos (DGI, taxation); none supervises virtual assets, since no legal framework exists.
Panama's Central Bank expects any licensed crypto financial institution to implement strong anti-money-laundering and KYC controls, including full due diligence on customers.
Canborsa offers up to 20x leverage on Uniswap for traders based in Panama.